Psoriasis is a chronic skin disorder, which means that it does not go away. Psoriasis patients have thick, pink or red skin patches covered in white or silvery scales. Plaques are dense, scaly patches. The severity of psoriasis varies greatly between individuals. It may be a minor irritation for some, but it can have a significant impact on the quality of life for others. Psoriasis treatment can help prevent flare-ups and reduce stress.
It usually appears in early adulthood, but it can occur later in life. Psoriasis can affect people of any age, gender, or race. It can improve and deteriorate over time. There are numerous Paid Plaque Psoriasis Clinical Trials in Michigan that may be able to assist you and countless others suffering from this condition.
What is the Pathophysiology of Psoriasis?
This condition happens when an overactive immune system accelerates skin cell growth. A month is enough time for normal skin cells to grow and shed (fall off). Skin cells in Psoriasis do this in three or four days. Instead of shedding, skin cells accumulate on the skin’s surface. Psoriasis plaques are believed to itch, burn, and sting some people. Plaques and scales can appear anywhere on the body, but they are most common on the elbows, knees, and scalp.
Psoriasis-related inflammation can affect other organs and tissues in the body. People who have Psoriasis may also have other health problems. People who have Psoriasis will sometimes develop Psoriatic Arthritis. PsA symptoms include swelling, stiffness, and pain in the joints and surrounding areas. PsA is frequently misdiagnosed, especially in its milder forms. However, it is critical to treat PsA as soon as possible to avoid permanent joint damage.
Symptoms typically appear between the ages of 15 and 25, but they can appear at any age. Psoriasis can affect men, women, and children of all skin colors.
What Causes/Triggers Psoriasis?
While there is no certainty about what causes Psoriasis, it is believed that the immune system and genetics play some important roles. Psoriasis genetics are complicated, and you can develop the disease even if you have no family history of it. A triggering event may alter the immune system, causing the onset of Psoriasis symptoms. Stress, illness (particularly streptococcal infections), skin injury, and certain medications are all common Psoriasis triggers.
The triggers for Psoriasis differ from person to person. What aggravates your Psoriasis may have no effect on someone else. The following are common Psoriasis triggers:
- Stress: One of the most common psoriasis triggers is stress. A Psoriasis flare-up can also be stressful. This may appear to be an endless loop. Relaxation techniques and stress management, on the other hand, may help prevent stress from affecting Psoriasis.
- Skin Injuries: Psoriasis can appear on skin that has been injured or harmed. This is due to the Koebner phenomenon, which states that scratches, sunburns, bug bites, and vaccinations can all cause a flare-up of Psoriasis.
- Illness: Psoriasis can be triggered by anything that affects the immune system. As a result, an ear infection, bronchitis, tonsillitis, or respiratory infection may cause a flare. Streptococcus infection (strep throat) is linked to Guttate Psoriasis, as it frequently causes the onset of Guttate Psoriasis in children.
It is possible to have strep throat and not exhibit any symptoms. If you’ve previously had strep throat, talk to your doctor about getting a strep throat test if your Psoriasis flares.
- Weather: A flare could be caused by the weather. Due to less sunlight and humidity, heated and drier indoor air, as well as stress and illness, cold weather can frequently cause psoriasis flares. Because of the natural sunlight and higher humidity, warm weather can often improve Psoriasis.
The Stress-Psoriasis Connection
Living with a chronic illness can be exhausting. This is especially true for visible conditions such as psoriasis. Psoriasis is an autoimmune disease that causes inflammation in the body as well as red, scaly, itchy skin patches. These patches are frequently visible in areas such as the knees, elbows, and scalp. While there is no cure for Psoriasis, Psoriasis treatment can help prevent flare-ups and reduce stress.
The relationship between stress and Psoriasis is complicated, and it works both ways. Psoriasis flares are known to be triggered by stress. People who develop these patches may be concerned about how psoriasis makes them look and feel.
Seeing Dermatologists and receiving the appropriate treatment can result in clearer skin and less stress. While your treatment is working, a counselor or other mental health provider will assist you in managing the emotional symptoms of psoriasis.
What are the Types of Psoriasis Based on their Location on the Body?
Psoriasis is classified into five types. It is possible to have multiple types of Psoriasis at the same time, as well as multiple types in a lifetime. Treatment options may differ depending on the type and location of Psoriasis.
Genital Psoriasis: Psoriasis of the genital area is very common. Two-thirds of people with Psoriasis will develop Genital Psoriasis at some point in their lives. The skin in the genital area, as well as the inner and upper thighs, can be affected by genital psoriasis.
Scalp Psoriasis: Scalp Psoriasis affects more than 60% of Psoriasis patients. The hairline, the forehead, the back of the neck, and the skin in and around the ears can all be affected by scalp Psoriasis.
Facial Psoriasis: One in every three people with psoriasis has Facial Psoriasis. It can affect any part of the face, including the brows, the skin between the nose and the upper lip, and the top of the forehead.
Hands, feet, and nails: Psoriasis can also affect the hands, feet, and nails. Psoriasis that affects the palms of the hands and/or the soles of the feet is known as Palmoplantar Psoriasis (PPP). Palmoplantar Psoriasis affects between 12% and 16% of Psoriasis patients. Nail changes can occur in up to 50% of people with Psoriasis.
Skin folds: Psoriasis can also affect skin folds such as those under the arms and breasts. Rubbing and sweating frequently irritate these areas.
How Can We Treat Psoriasis?
There is no cure for this complex skin condition. Psoriasis treatments can:
- Reduce scales and inflammation due to Psoriasis,
- Slow down skin cell growth, and
- Help with the removal of plaques.
There are three types of Psoriasis treatments:
Topical therapies: Creams and ointments applied directly to the skin can aid in the treatment of mild to moderate Psoriasis. These include topical corticosteroids, vitamin D supplements, topical retinoids, salicylic acid, and moisturizers.
Systemic medication: People with moderate to severe Psoriasis, as well as those who have not responded well to other types of treatment, may require oral or injected medications. Because many of these medications have serious side effects, doctors usually prescribe them for short periods of time.
Among these medications are Cyclosporine, Methotrexate, Biologics, and Oral retinoids.
Light therapy: This Psoriasis treatment involves the use of ultraviolet (UV) or natural light. The sun kills overactive white blood cells that attack healthy skin cells and cause rapid cell growth. UVA and UVB light may both be beneficial in reducing the symptoms of mild to moderate Psoriasis.
A combination of treatments will benefit the majority of people with moderate to severe Psoriasis. This therapy involves more than one type of treatment to relieve the symptoms. Some people may use the same treatment for the rest of their lives. Others may need to switch treatments on occasion if their skin stops responding to the current treatment.
Psoriasis is an itchy skin condition that can appear and disappear throughout your life. It is caused by an overactive immune system and is not contagious. Although there is no cure for Psoriasis, Psoriasis treatments can alleviate symptoms. Your doctor may recommend a special cream, moisturizer, or medications. If creams or medications do not work, there are other options. Maintaining your overall health will also aid in the improvement of symptoms. There is multiple Clinical Research in Michigan that is dedicated to conducting Clinical Trials to aid in the discovery of a potential treatment for many skin conditions like Psoriasis.